Tesis: Recent submissions
Now showing items 521-540 of 611
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Polimorfismos en el gen de la y-glutamil hidrolasa y respuesta al metotrexato en leucemia linfoblástica aguda en México
(Universidad Autónoma de Guerrero (México), 2009-08)This study evaluated the association of -401C/T and +452C/T polymorphisms of y-glutamyl hydrolase and the lack of response to methotrexate in acute lymphoblastic leukemia. Genotyping was performed 70 children with acute ... -
Expresión de COX-2, MMP-9 y VEGF en lesiones premalignas de cérvix uterino e infección por el virus del papiloma humano
(Universidad Autónoma de Guerrero (México), 2009-11)Low-grade (LSIL) and high-grade (HSIL) squamous intraepithelial lesions represent premalignant stages of cervical cancer. Cervical cancer represents the first cause of cancer-associated deaths among Mexican women. Chronic ... -
Polimorfismos +1444 c/t y +1846 g/a del gen de la proteína C reactiva y su asociación con los niveles de su proteína en personas con obesidad
(Universidad Autónoma de Guerrero (México), 2009-08)Several single nucleotide polymorphisms (SNPs) in the C reactive protein gene (CRP) have been associated with increase serum concentration of their protein, some of them have been correlated with cardiovascular disease. ... -
Daño genotóxico en linfocitos humanos expuestos in vitro a la mezcla de permetrina-aletrina
(Universidad Autónoma de Guerrero (México), 2010-03)Pyrethroids are synthetic insecticides widely used in public health programs and in agriculture. In developing countries a mixture of the pyrethroids permethrin and allethrin is used as space spray to control the overpopulation ... -
Expresión de COX-2 en entamoeba histolytica durante la interacción trofozoíto-fibronectina
(Universidad Autónoma de Guerrero (México), 2019-11)Recently it has been demonstrated that Entamoeba histolytica synthesizes mRNA and COX-2 like protein during the production of liver abscesses in hamsters. Also, PGE2 synthesis in the trophozoites has been reported as an ... -
Expresion de telomerasa, KI-67 y el Virus del Papiloma Humano oncogénico en neoplasias intraepiteliales cervicales
(Universidad Autónoma de Guerrero (México), 2009-10)Evaluate the relationship between Ki-67 and telomerase expression with CIN grade and the physical state of high risk human papillomavirus (HR-HPV) DNA. Methods. An observational comparative study was done of 80 fragments ... -
GTPasas RhoA, Rac1 y Cdc42 y los GEFs Tiam1 y BPix en el desarrollo de cáncer cervicouterino
(Universidad Autónoma de Guerrero (México), 2009-09)Cervical cancer is an important health problem and one of the major causes of mortality in Mexico particularly in some states with high rates of exclusion, including the state of Guerrero. Fortunately, advances in molecular ... -
Polimorfismos A19G en el gen de leptina y A668G en su receptor y su relación con las concentraciones de leptina sérica y la hiperfagia en niños con obesidad
(Universidad Autónoma de Guerrero (México), 2009-09)Leptin is an anorexigenic hormone that controls food intake and energy homeostasis, which by binding to its receptors in the hypothalamus, releases signals that generates a feeling of satiety, regulating appetite and weight ... -
Participación de mTOR en la regulación del transportador EAAC1 en células C6 de Glioma
(Universidad Autónoma de Guerrero (México), 2009-08)Glutamate (Glu) is the major excitatory neurotransmitter in the vertebrate central nervous system (CNS); it is involved in neural plasticity as well in learning and memory. Neuronal and glial sodium-dependent transporters ... -
Efecto de la sobreexpresión de miR-23b en los niveles de fosforilación de Gab1 y FAK vía c-Met y en la migración e invasión en líneas celulares de cáncer cervico uterino
(Universidad Autónoma de Guerrero (México), 2019-01)Cervical uterine cancer (CaCU) is the second most frequent cancer in women and persistent infection by HPV-AR is the main risk factor for its onset. Epigenetic factors such as the deregulated expression of microRNAs (miRNAs) ... -
Efecto de las variantes comunes en los genes SLC22A1 y SLC22A2 sobre el control glicémico de pacientes con diabetes tipo 2 tratados con metformina
(Universidad Autónoma de Guerrero (México), 2019-01)The organic cation transporters (OCT1 and OCT2) and the multidrug and toxin extrusiontransporter 1 (MATE1), encoded by the SLC22A1, SLC22A2, and SLC47A1 genes, respectively, are responsible for the absorption of the metformin ... -
Marcadores de disfunción endotelial asociados con riesgo cardiovascular en jóvenes con obesidad y peso normal
(Universidad Autónoma de Guerrero (México), 2013-10)Obesity promotes endothelial dysfunction causing the detachment of endothelial cells and overexpression of cell adhesion molecules. Objective. To evaluate the ratio of the number of circulating endothelial cells and levels ... -
Análisis proteómico en tejidos de cáncer epitelial de ovario de pacientes resistentes a la quimioterapia de primera línea
(Universidad Autónoma de Guerrero (México), 2013-10)The agents of platinum and taxanes are the standard chemotherapy to treat ovarian epithelial cancer for more than 30 years, however, 70% of patients have resistance to these medications. In an effort to identify the cellular ... -
Polimorfismos -511 T/C, -31 C/T y 3954 C/T de IL-1B en enfermedad periodontal en población guerrerense
(Universidad Autónoma de Guerrero (México), 2013-10)The polymorphisms -511 T/C, -31 C/T and +3954 C/T of IL-1B gene are associated with the induction of inflammation and have been associated with the risk for developing periodontal disease. The aim of this work was to ... -
Evaluación de la inmunogenicidad y efecto protector de la vacuna oral S3Pvac-papaya contra la cisticercosis en cerdos
(Universidad Autónoma de Guerrero (México), 2014-01)Neurocysticercosis is a parasitic disease caused by the establishment of the larval stage of Taenia solium, which can be established in humans or pigs. Among the proposed control interventions include prevention of porcine ... -
Expresión de lumican, a-sma y ciclina D1 y su asociación con E6 del VPH de alto riesgo en lesiones premalignas y carcinoma cervical
(Universidad Autónoma de Guerrero (México), 2019-01)The persistence and integration of HR-HPV, increase the risk of progression of squamous intraepithelial lesions (SIL) to invasive cervical carcinoma (CCI). The E6 protein of HR-HPV, plays an important role in cell ... -
Relación entre los grupos filogenéticos y factores de virulencia en Escherichia coli uropatógena en dos localidades en México
(Universidad Autónoma de Guerrero (México), 2014-10)Uropathogenic Escherichia coli (UPEC) is the major causative agent of urinary tract infections (UTI) and virulence factors are responsible for the severity of these emerging infections. The aim of this study was to evaluate ... -
Expresión de E-cadherina, SMA, Hic-5 y su correlación con el índice pronóstico Nottingham (IPN) en cáncer de mama
(Universidad Autónoma de Guerrero (México), 2018-11)Breast cáncer (BrCa) is a heterogeneous disease that includes different molecular characteristics, behavior, morphological appearance and response to therapy. The routine clinical follow-up of patients with BrCa includes ... -
Actividad y polimorfismos en SOD y GST y su relación con ADNmt en fumigadores
(Universidad Autónoma de Guerrero (México), 2018-03)Organophosphorus pesticides, carbamates and pyrethroids are the most used pesticides in Mexico for the control of vectors; although it has been reported that these can cause health damage associated with their toxic ... -
Estudio de la interacción de la dieta con polimorfismos en los genes LEPR, APOA2 y APOA5 y su relación con la obesidad y dislipidemias en jóvenes
(Universidad Autónoma de Guerrero (México), 2014-12)Diet is an important environmental factor that interacts with genes to modulate the likelihood of developing disorders in lipid metabolism and their involvement in the presence of other chronic diseases such as obesity. ...