Doctorado: Recent submissions
Now showing items 61-80 of 111
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miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer
(Infectious Agents and Cancer, 2015-01)The aberrant expression of miR-23b is involved in the development and progression of cancer. The aim of this study was to evaluate the potential role of methylation in the silencing of miR-23b in cervical cancer celllines ... -
Diversidad de los genotipos vacA y cagA de helicobacter pylori y expresión de interferón gamma en pacientes con gastritis crónica y cáncer gástrico
(Revista de Gastroenterología de México, 2014-11-26)Background: Helicobacter pylori (H. pylori) is the main risk factor for the development of chronic gastritis, gastric ulcer, and gastric cancer. In H. pylori-infected individuals, the clinical result is dependent on various ... -
The gerW protein Is not involved in the germination of spores of bacillus species
(PLoS ONE, 2015-03-19)Germination of dormant spores of Bacillus species is initiated when nutrient germinants bind to germinant receptors in spores' inner membrane and this interaction triggers the reléase of dipicolinic acid and cations from ... -
DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation
(American Journal of Cancer Research, 2017-01)Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo methyltransferase, is clearly related to abnormal methylation of tumour suppressor genes, DNA repair ... -
Changes in global gene expression profiles induced by HPV16 E6 oncoprote invariants incervical carcinoma C33-Acells
(Virology, 2015-12-02)We analyzed the effects of the expression of HPV 16 E6 oncoprotein variants (AA-a, AA-c, E-A176/G350, E-C188/G350, E-G350), and the E-Prototype in global gene expression profiles in an in vitro model. E6 gene was cloned ... -
Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions
(Oncology Letters, 2017-09-13)High-risk human papillomavirus (HPV) is the primary cause of cervical carcinoma (CC). Viral integration into the host chromosomes is associated with neoplastic progression, and epigenetic changes may occur as a result. The ... -
Effects of sporulation conditions on the germination and germination protein levels of bacillus subtilis spores
(Applied and Environmental Microbiology, 2012-02-10)Bacillus subtilis spores prepared in rich medium germinated faster with nutrient germinants than poor-medium spores as populations in liquid and multiple individual spores on a microscope slide. Poor-medium spores had ... -
The effects of heat activation on bacillus spore germination, with nutrients or under high pressure, with or without various germination proteins
(Applied and Environmental Microbiology, 2015-02-13)Nutrient germination of spores of Bacillus species occurs through germinant receptors (GRs) in spores'inner membrane (IM) in a process stimulated by sublethal heat activation. Bacillus subtilis spores maximum germination ... -
Polymorphisms in the LPL and CETP genes and haplotype in the ESR1 gene are associated with metabolic syndrome in women from Southwestern México
(International Journal of Molecular Sciences, 2015-09-08)Metabolic syndrome (MetS) is a combination of metabolic disorders associated with an increased risk for cardiovascular disease (CVD). Studies in women reported associations between polymorphisms in ESR1, LPL and CETP genes ... -
Correlation of leptin and soluble leptin receptor levels with anthropometric parameters in mother-newborn pairs
(International Journal of Clinical and Experimental Medicine, 2015-07-30)The aim of this study was to investigate if anthropometric parameters are associated with both leptin and soluble leptin receptor (sLEPR) levels in newborns and their mothers. This cross-sectional study was performed in ... -
Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review)
(2014-03-13)Cancer is a complex disease caused by genetic and epigenetic abnormalities that affect gene expression. The progression from precursor lesions to invasive cervical cancer is influenced by persistent human papilloma virus ... -
Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico
(Virology Journal, 2015-02-22)HPV 16 is the cause of cervical carcinoma, but only a small fraction of women with HPV infection progress to this pathology. Besides persistent infection and HPV integration, several studies have suggested that HPV intratype ... -
Macrophage migration inhibitory factor promoter polymorphisms (-794 CATT5 and -173 G>C): relationship with mRNA expression and soluble MIF levels in young obese subjects
(Hindawi Publishing Corporation, 2015-03-30)We analyzed the relationship of -794 CATT5 and -173 G>C MIF polymorphisms with mRNA and soluble MIF in young obese. A total of 250 young subjects, 150 normal-weight and 100 obese subjects, were recruited in the study. ... -
Leptin induces partial epithelial-mesenchymal transition in a FAK-ERK dependent pathway in MCF10A mammary non-tumorigenic cells
(Clin Exp Pathol, 2017-10-15)Epithelial-mesenchymal transition (EMT) is a biological process involved in different steps of tumor progression and metastasis of breast cancer cells. Epidemiological studies suggest a link between obesity and the progression ... -
Differential proteins among normal cérvix cells and cervical cancer cells with HPV-16 infection, through mass spectrometrybased Proteomics (2D-DIGE) in women from Southern México
(Proteome Science, 2016-09-05)Cervical cancer (CC) is the fourth most common cancer in women worldwide with an estimated 528,000 new cases in 2012. The same year México had an incidence of 13,960 and a mortality of 4769 cases. There are several diagnosis ... -
Risk of progression of early cervical lesions is associated with Integration and persistence of HPV-16 and expression of E6, Ki-67, and telomerase)
(2015-09-04)Low-grade squamous intraepithelial lesions (LSIL) are the earliest lesions of the uterine cervix, the persistence and integration of high-risk human papillomavirus (HR-HPV) as type 16, which promotes the development of ... -
MicroRNA miR-16-1 regulates CCNE1 (cyclin E1) gene expression in human cervical cancer cells
(International Journal of Clinical and Experimental Medicine, 2015-09-30)MicroRNAs are involved in diverse biological processes through regulation of gene expression. The microRNA profile has been shown to be altered in cervical cancer (CC). MiR-16-1 belongs to the miR-16 cluster and has been ... -
Variaciones de número de copias: marcadores y predictores de diabetes tipo 2
(Revista Medica Instituto Mexicano Seguro Social, 2014-07-15)Type 2 diabetes (T2D) is a disease characterized by a defi ciency in production or action of insulin. It is the result mainly of the interaction of the environment, lifestyle, as well as genetic factors. It is considered ... -
Resistencia a la insulina inducida por exposición a metamidofos: participación del estrés oxidativo
(Universidad Autónoma de Guerrero (México), 2018-01)Insulin resistance (IR) is the incapacity observed in tissues for responding to biological activity induce by insulin stimulation; this condition has been linked with the development of several chronic diseases. The causes ... -
Modelo de fachada vegetada en el clima aw (clasificación köppen): Acapulco, guerrero
(Universidad Autónoma de Guerrero (México), 2016-09)This research shows the performance analysis model vegetated facade in the context of climate (Aw) warm moist through the use of indicators of sustainable green infrastructure. The results showed significant environmental, ...