Efecto de la metformina sobre marcadores bioquímicosmoleculares y secreción de exosomas en células HUH7 con resistencia a insulina.

Abstract

Liver-specific insulin resistance is associated with the development of the main challenges in metabolism resulting in dyslipidemia, hyperinsulinemia and hyperglycemia. In vitro models developed for researching the hepatic insulin resistance are limited and employed cell lines without similar characteristics to primary human hepatocytes.